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Studies on the subject of “skin and hair”.
Summarized studies and original literature for you to download free of charge.
Study
impact of airborne pollution on ski
E Araviiskaia , E Berardesca , T Bieber , G Gontijo , M Sanchez Viera , L Marrot , B Chuberre , B Dreno
Abstract: Indoor and outdoor air pollutants are changing our environment and pose a growing threat to human Health worldwide. The effects of air pollution on respiratory and cardiac health and disease are well established, but its effects on the skin are poorly characterized. Nevertheless, the skin is one of the main targets of pollutants that reach the superficial and deeper layers of the skin by transcutaneous and systemic routes. In this review, we report the results of basic and clinical research studies monitoring contaminant concentrations in human tissues, including skin and hair.
study
The therapeutic effect and the changed serum zinc level after zinc supplementation in alopecia areata patients who had a low serum zinc level
Hoon Park , Chul Woo Kim, Sang Seok Kim, Chun Wook Park
Abstract: High-dose oral zinc gluconate was administered to patients with alopecia areata over a period of 12 weeks without any other concomitant treatment. After therapy, serum zinc levels increased significantly. Positive therapeutic effects were observed in 9 out of 15 patients (66.7%), although this was not statistically significant. Results suggest that in alopecia areata patients with low serum zinc levels, zinc supplementation may provide supportive therapy when traditional therapeutic methods have been unsuccessful.
Study
Oral supplementation with specific bioactive collagen peptides improves nail growth and reduces symptoms of brittle nails.
Doris Hexsel , Vivian Zague 2 , Michael Schunck , Carolina Siega , Fernanda O Camozzato , Steffen Oesser
Abstract: Brittle nail syndrome is a common problem in women and refers to nails that exhibit surface roughness, fraying and detachment…. This study investigated whether daily oral supplementation of collagen peptides alleviates the symptoms of brittle nails and improves nail growth rate….. 25 participants took 2.5 g of specific bioactive collagen peptides (BCP, VERISOL®) once daily for 24 weeks, followed by a 4-week break in therapy. The nail growth rate and the frequency of cracked and/or broken nails as well as an assessment of symptoms and the total score of clinical improvement of brittle nails were evaluated by a physician during treatment and 4 weeks after discontinuation….. This study showed that daily use of BCP increased nail growth and improved brittle nails in conjunction with a significant decrease in the incidence of nail breakage.
Study
Dietary Supplementation with Specific Collagen Peptides Has a Body Mass Index-Dependent Beneficial Effect on Cellulite Morphology.
Michael Schunck , Vivian Zague , Steffen Oesser , Ehrhardt Proksch
Abstract : This double-blind, placebo-controlled clinical trial investigated the efficacy of specific bioactive collagen peptides (BCP) in the treatment of cellulite in normal and overweight women. A total of 105 women aged 24 to 50 years with moderate cellulite were randomized to receive a daily dose of 2.5 g BCP or a placebo orally for 6 months. The degree of cellulite was assessed before the start of treatment and after 3 and 6 months. In addition, skin waviness, skin density and the length of the subcutaneous borderline were assessed. The results of the study showed that regular use of BCP over a period of 6 months led to a significant improvement in the appearance of the skin in women with moderate cellulite. Based on the current data, it can be concluded that long-term therapy with orally administered BCP leads to an improvement in cellulite and has a positive effect on skin health.
Study
Zinc Deficiency Associated with Hypothyroidism: An Overlooked Cause of Severe Alopecia
Ambooken Betsy, MP Binitha, and S Sarita
Abstract/Case report: Hypothyroidism is a common and recognized cause of diffuse hair loss. Zinc and other trace elements such as copper and Selenium are required for the synthesis of thyroid hormones, a deficiency of which can lead to hypothyroidism. Conversely, thyroid hormones are essential for the absorption of Zinc, and therefore hypothyroidism can lead to acquired Zinc deficiency. In the patients studied, zinc deficiency may have contributed significantly to the development of hypothyroidism. Mental depression, taste acuity, appetite, skin lesions and hair loss showed a dramatic improvement not when thyroxine treatment was started, but when zinc supplementation was given.
Study
Age-induced hair greying – the multiple effects of oxidative stress
M Seiberg
Abstract: An obvious sign of aging is graying of the hair or loss of pigment production and deposition in the hair shafts. Numerous mechanisms acting at different levels and follicular sites contribute to hair graying, from melanocyte stem cell defects to follicular melanocyte death. A central problem common to these processes is oxidative damage. In the hair follicle stem cell niche, oxidative stress, accelerated by depletion of the B-cell lymphoma 2 gene (BCL-2), leads to selective apoptosis and reduction of melanocyte stem cells, reducing repopulation of newly formed anagen follicles
Study
Analysis of serum zinc and copper concentrations in hair loss.
Min Seong Kil, Chul Woo Kim , Sang Seok Kim
Abstract: Trace elements such as Zinc and copper play a significant role in many forms of hair loss. However, the effect of Zinc and copper on the pathogenesis of hair loss is still unknown…. The purpose of this study is to evaluate Zinc and copper status in each of the four types of hair loss…. Zinc and copper serum concentrations were evaluated between the control group and each of the four types of hair loss patients….. In all patients with hair loss, the mean serum zinc level was significantly lower than in the control group, while the serum copper level was not significantly different… … Analysis of each group showed that all groups with hair loss had statistically lower zinc concentrations but no copper concentrations……The data led to the hypothesis that disturbances in zinc metabolism play a key role in hair loss…. while the effect of copper on hair growth and hair loss cycles needs further investigation.
Study
The Role of Vitamins and Minerals in Hair Loss: A Review
Hind M Almohanna, Azhar A Ahmed, John P Tsatalis, Antonella Tosti
Abstract: There are several reasons to suspect a role for micronutrients in non-scarring alopecia. Micronutrients are important elements in the normal hair follicular cycle and play a role in cell turnover, often occurring in the rapidly dividing matrix cells in the follicular bulb. The treatment of alopecia is an essential aspect of clinical dermatology given the prevalence of hair loss and its significant impact on patients’ quality of life. The role of nutrition and diet in the treatment of hair loss represents a dynamic and growing area of research. In this review, we summarize the role of vitamins and minerals such as vitamin A, vitamin B, vitamin C, vitamin D, vitamin E, iron, Selenium and Zinc in non-scarring alopecia. ….. Micronutrients such as vitamins and minerals play an important but not entirely clear role in the normal development of hair follicles and the function of immune cells. Deficiencies of such micronutrients may represent a modifiable risk factor associated with the development, prevention and treatment of alopecia…